Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany

BACKGROUND: Risk stratification for lung cancer (LC) screening is so far mostly based on smoking history. This study aimed to assess if and to what extent such risk stratification could be enhanced by additional consideration of genetic risk scores (GRSs) and epigenetic risk scores defined by DNA me...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Yu, Haixin, Raut, Janhavi R., Schöttker, Ben, Holleczek, Bernd, Zhang, Yan, Brenner, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301507/
https://ncbi.nlm.nih.gov/pubmed/32552915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00872-y
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