miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway

The adult Leydig cells (ALCs), originated from stem Leydig cells (SLCs), can secrete testosterone which is essential for germ cell development and sexual behavior maintenance. As a synthetic compound, ethane dimethane sulfonate (EDS), a well-known alkylating agent, has been reported to specifically...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Cui, Yang, Chen, Rui, Ma, Lin, Yang, Wenjing, Chen, Mingyue, Zhang, Yanghai, Yu, Shuai, Dong, Wuzi, Zeng, Wenxian, Lan, Xianyong, Pan, Chuanying
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300349/
https://ncbi.nlm.nih.gov/pubmed/32596241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00448
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