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Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options

Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide. Despite the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of epileptic seizures, about one-third of patients with epilepsy have seizures refractory to pharmacotherapy. Patients with...

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Podrobná bibliografie
Vydáno v:Pharmacol Rev
Hlavní autoři: Löscher, Wolfgang, Potschka, Heidrun, Sisodiya, Sanjay M., Vezzani, Annamaria
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300324/
https://ncbi.nlm.nih.gov/pubmed/32540959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.120.019539
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