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Microtubule Simulations Provide Insight into the Molecular Mechanism Underlying Dynamic Instability

The dynamic instability of microtubules (MTs), which refers to their ability to switch between polymerization and depolymerization states, is crucial for their function. It has been proposed that the growing MT ends are protected by a “GTP cap” that consists of GTP-bound tubulin dimers. When the spe...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Tong, Dudu, Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300308/
https://ncbi.nlm.nih.gov/pubmed/32413312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.028
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