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Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a prolonged QT interval. Therefore, QT prolonga...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Wang, Hui, Wang, Cao, Lu, Yuan, Yan, Yan, Leng, Dongjing, Tian, Shanshan, Zheng, Dongjie, Wang, Zhiguo, Bai, Yunlong
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300225/
https://ncbi.nlm.nih.gov/pubmed/32595491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00614
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