Cirrhotic Endothelial Progenitor Cells Enhance Liver Angiogenesis and Fibrosis and Aggravate Portal Hypertension in Bile Duct-Ligated Cirrhotic Rats

BACKGROUND: Circulating cirrhotic endothelial progenitor cells (EPC) interact with both liver sinusoidal endothelial cells (LSEC) and hepatic stellate cells (HSC) and promote angiogenesis in vitro. This study evaluated the effect of cirrhotic and control EPCs on hepatic angiogenesis, microcirculatio...

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Udgivet i:Front Physiol
Main Authors: Tripathi, Dinesh Mani, Hassan, Mohsin, Siddiqui, Hamda, Kaur, Impreet, Rawal, Preety, Bihari, Chaggan, Kaur, Savneet, Sarin, Shiv K.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7300214/
https://ncbi.nlm.nih.gov/pubmed/32595520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00617
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