Á lódáil...
Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity
P-glycoprotein (P-gp, ABCB1) overexpression is, currently, one of the most important multidrug resistance (MDR) mechanisms in tumor cells. Thus, modulating drug efflux by P-gp has become one of the most promising approaches to overcome MDR in cancer. Yet, more insights on the molecular basis of drug...
Na minha lista:
| Foilsithe in: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2020
|
| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7300024/ https://ncbi.nlm.nih.gov/pubmed/32555203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66587-5 |
| Clibeanna: |
Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!
|