Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis

Cryptococcal meningoencephalitis (CM) is the major cause of infection-related neurological death, typically seen in immunocompromised patients. However, T cell–driven inflammatory response has been increasingly implicated in lethal central nervous system (CNS) immunopathology in human patients and m...

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Udgivet i:Sci Adv
Main Authors: Xu, Jintao, Neal, Lori M., Ganguly, Anutosh, Kolbe, Jessica L., Hargarten, Jessica C., Elsegeiny, Waleed, Hollingsworth, Christopher, He, Xiumiao, Ivey, Mike, Lopez, Rafael, Zhao, Jessica, Segal, Benjamin, Williamson, Peter R., Olszewski, Michal A.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299622/
https://ncbi.nlm.nih.gov/pubmed/32596454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba2502
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