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miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma

Despite significant development of melanoma therapies, death rates remain high. MicroRNAs, controlling posttranscriptionally gene expression, play role in development of resistance to BRAF inhibitors. The aim of the study was to assess the role of miR-410-3p in response to vemurafenib–BRAF inhibitor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Grzywa, Tomasz M., Klicka, Klaudia, Paskal, Wiktor, Dudkiewicz, Julia, Wejman, Jarosław, Pyzlak, Michał, Włodarski, Paweł K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299409/
https://ncbi.nlm.nih.gov/pubmed/32555626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234707
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