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Genome engineering of induced pluripotent stem cells to manufacture natural killer cell therapies
Natural killer (NK) cells play a crucial role in host immunity by detecting cells that downregulate MHC class I presentation and upregulate stress ligands, as commonly seen in cancers. Current NK therapies using primary NK cells are prone to manufacturing issues related to expansion and storage. Alt...
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| Udgivet i: | Stem Cell Res Ther |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7298853/ https://ncbi.nlm.nih.gov/pubmed/32546200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01741-4 |
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