Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients

BACKGROUND: Cerebral metabolic rate of oxygen (CMRO(2)), a measure of global oxygen metabolism, reflects resting cellular activity. The mechanisms underlying fatigue and cognitive dysfunction in multiple sclerosis (MS) remain unknown. If fatigue indeed reflects ongoing autoimmune activity and cortic...

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Dades bibliogràfiques
Publicat a:Neuroimage Clin
Autors principals: West, Kl., Sivakolundu, Dk., Maruthy, Gb., Zuppichini, Md., Liu, P., Thomas, Bp., Spence, Js., Lu, H., Okuda, Dt., Rypma, B.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298673/
https://ncbi.nlm.nih.gov/pubmed/32544855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102281
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