Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model

Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory agents are currently under investigation as they demonstrated to alleviate symptoms in patients having IDD. However,...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Bioeng Biotechnol
Autori principali: Li, Zhen, Gehlen, Yannik, Heizmann, Fabian, Grad, Sibylle, Alini, Mauro, Richards, R. Geoff, Kubosch, David, Südkamp, Norbert, Izadpanah, Kaywan, Kubosch, Eva Johanna, Lang, Gernot
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Bioengineering and Biotechnology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7298127/
https://ncbi.nlm.nih.gov/pubmed/32587853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00583
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