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Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but not low-risk rats

Opioid addiction has been declared a public health emergency, with fatal overdoses following relapse reaching epidemic proportions and disease-associated costs continuing to escalate. Relapse is often triggered by re-exposure to drug-associated cues, and though the neural substrates responsible for...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: O’Neal, Timothy J., Nooney, Marlaena N., Thien, Katie, Ferguson, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297977/
https://ncbi.nlm.nih.gov/pubmed/31747681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0571-9
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