The deubiquitylase UCHL3 maintains cancer stem-like properties by stabilizing the aryl hydrocarbon receptor

Cancer stem cells (CSCs) exhibit highly aggressive and metastatic features and resistance to chemotherapy and radiotherapy. Aryl hydrocarbon receptor (AhR) expression varies among non-small cell lung cancers (NSCLCs), and the mechanisms that support abnormal AhR expression in CSCs remain elusive. He...

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I publikationen:Signal Transduct Target Ther
Huvudupphovsmän: Ouyang, Lianlian, Yan, Bin, Liu, Yating, Mao, Chao, Wang, Min, Liu, Na, Wang, Zuli, Liu, Shouping, Shi, Ying, Chen, Ling, Wang, Xiang, Cheng, Yan, Cao, Ya, Xiao, Desheng, Zhang, Lingqiang, Liu, Shuang, Tao, Yongguang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297794/
https://ncbi.nlm.nih.gov/pubmed/32546741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0181-3
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