The deubiquitylase UCHL3 maintains cancer stem-like properties by stabilizing the aryl hydrocarbon receptor

Cancer stem cells (CSCs) exhibit highly aggressive and metastatic features and resistance to chemotherapy and radiotherapy. Aryl hydrocarbon receptor (AhR) expression varies among non-small cell lung cancers (NSCLCs), and the mechanisms that support abnormal AhR expression in CSCs remain elusive. He...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Ouyang, Lianlian, Yan, Bin, Liu, Yating, Mao, Chao, Wang, Min, Liu, Na, Wang, Zuli, Liu, Shouping, Shi, Ying, Chen, Ling, Wang, Xiang, Cheng, Yan, Cao, Ya, Xiao, Desheng, Zhang, Lingqiang, Liu, Shuang, Tao, Yongguang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297794/
https://ncbi.nlm.nih.gov/pubmed/32546741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0181-3
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