Peli1 signaling blockade attenuates congenital zika syndrome

Zika virus (ZIKV) infects pregnant women and causes devastating congenital zika syndrome (CZS). How the virus is vertically transmitted to the fetus and induces neuronal loss remains unclear. We previously reported that Pellino (Peli)1, an E3 ubiquitin ligase, promotes p38MAPK activation in microgli...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Luo, Huanle, Li, Guangyu, Wang, Binbin, Tian, Bing, Gao, Junling, Zou, Jing, Shi, Shuizhen, Zhu, Shuang, Peng, Bi-Hung, Adam, Awadalkareem, Martinez, Ariza, Hein, Kimberly, Winkelmann, Evandro R., Mahmoud, Yoseph, Zhou, Xiaofei, Shan, Chao, Rossi, Shannan, Weaver, Scott, Barrett, Alan D. T., Sun, Shao-Cong, Zhang, Wenbo, Shi, Pei-Yong, Wu, Ping, Wang, Tian
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297310/
https://ncbi.nlm.nih.gov/pubmed/32544190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008538
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