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Prolonging the Reduction of Nicotine Self-Administration in Rats by Coadministering Chronic Nicotine With Amitifadine, a Triple Monoamine Reuptake Inhibitor With CYP2B6 Inhibitory Actions

INTRODUCTION: Existing treatments can aid tobacco smoking cessation, but they have low efficacy. Because there is a network of neural systems involved in tobacco addiction, combination treatments may provide greater efficacy. Chronic nicotine and amitifadine have each been shown to significantly red...

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Bibliographic Details
Published in:Nicotine Tob Res
Main Authors: Levin, Edward D, Wells, Corinne, Slade, Susan, Lee, Michelle, McKinney, Anthony A, Rose, Jed E, Rezvani, Amir H
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297093/
https://ncbi.nlm.nih.gov/pubmed/31187118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntz054
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