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Specialization of mucosal immunoglobulins in pathogen control and microbiota homeostasis occurred early in vertebrate evolution
While mammalian secretory IgA (sIgA) targets mucosal pathogens for elimination, its interaction with the microbiota also enables commensal colonization and homeostasis. This paradoxical requirement in the control of pathogens versus microbiota raised the question of whether mucosal (secretory) immun...
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| Publicado no: | Sci Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7296778/ https://ncbi.nlm.nih.gov/pubmed/32034088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aay3254 |
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