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Toll-like Receptor 4 Stimulates Gene Expression via Smad2 Linker Region Phosphorylation in Vascular Smooth Muscle Cells

[Image: see text] Atherosclerosis begins in the vessel wall with the retention of low density lipoproteins to modified proteoglycans with hyperelongated glycosaminoglycan (GAG) chains. Bacterial infections produce endotoxins such as lipopolysaccharide that exacerbate the outcome of atherosclerosis b...

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Publicat a:ACS Pharmacol Transl Sci
Autors principals: Afroz, Rizwana, Zhou, Ying, Little, Peter J., Xu, Suowen, Mohamed, Raafat, Stow, Jennifer, Kamato, Danielle
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296535/
https://ncbi.nlm.nih.gov/pubmed/32566917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00113
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