Toll-like Receptor 4 Stimulates Gene Expression via Smad2 Linker Region Phosphorylation in Vascular Smooth Muscle Cells

[Image: see text] Atherosclerosis begins in the vessel wall with the retention of low density lipoproteins to modified proteoglycans with hyperelongated glycosaminoglycan (GAG) chains. Bacterial infections produce endotoxins such as lipopolysaccharide that exacerbate the outcome of atherosclerosis b...

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Foilsithe in:ACS Pharmacol Transl Sci
Main Authors: Afroz, Rizwana, Zhou, Ying, Little, Peter J., Xu, Suowen, Mohamed, Raafat, Stow, Jennifer, Kamato, Danielle
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296535/
https://ncbi.nlm.nih.gov/pubmed/32566917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00113
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