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Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20

Chemokines are important protein-signaling molecules that regulate various immune responses by activating chemokine receptors which belong to the G protein-coupled receptor (GPCR) superfamily. Despite the substantial progression of our structural understanding of GPCR activation by small molecule an...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wasilko, David Jonathan, Johnson, Zachary Lee, Ammirati, Mark, Che, Ye, Griffor, Matthew C., Han, Seungil, Wu, Huixian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295996/
https://ncbi.nlm.nih.gov/pubmed/32541785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16820-6
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