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Human cytomegalovirus pp65 peptide-induced autoantibodies cross-reacts with TAF9 protein and induces lupus-like autoimmunity in BALB/c mice

Human cytomegalovirus (HCMV) has been linked to the triggering of systemic lupus erythematosus (SLE). We proposed that B cell epitope region of HCMV phosphoprotein 65 (HCMVpp65)(422–439) mimics an endogenous antigen and initiates lupus-like autoimmunity. Amino acid homology between HCMVpp65(422-439)...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Hsieh, Ao-Ho, Kuo, Chang-Fu, Chou, I-Jun, Tseng, Wen-Yi, Chen, Yen-Fu, Yu, Kuang-Hui, Luo, Shue-Fen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295797/
https://ncbi.nlm.nih.gov/pubmed/32541894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66804-1
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