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Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry

Transcription factors (TFs) regulate target genes by specific interactions with DNA sequences. Detecting and understanding these interactions at the molecular level is of fundamental importance in biological and clinical contexts. Crosslinking mass spectrometry is a powerful tool to assist the struc...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Reim, Alexander, Ackermann, Roland, Font-Mateu, Jofre, Kammel, Robert, Beato, Miguel, Nolte, Stefan, Mann, Matthias, Russmann, Christoph, Wierer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295792/
https://ncbi.nlm.nih.gov/pubmed/32541649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16837-x
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