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Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth
Breast cancer brain metastases (BCBM) have a 5-20 year latency and account for 30% of mortality; however, mechanisms governing adaptation to the brain microenvironment remain poorly defined. We combine time-course RNA-sequencing of BCBM development with a Drosophila melanogaster genetic screen, and...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7295786/ https://ncbi.nlm.nih.gov/pubmed/32541798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16832-2 |
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