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Tumor spheroids under perfusion within a 3D microfluidic platform reveal critical roles of cell-cell adhesion in tumor invasion

Tumor invasion within the interstitial space is critically regulated by the force balance between cell-extracellular matrix (ECM) and cell-cell interactions. Interstitial flows (IFs) are present in both healthy and diseased tissues. However, the roles of IFs in modulating cell force balance and subs...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Huang, Yu Ling, Ma, Yujie, Wu, Cindy, Shiau, Carina, Segall, Jeffrey E., Wu, Mingming
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295764/
https://ncbi.nlm.nih.gov/pubmed/32541776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66528-2
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