β-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2

During bone marrow stromal cell (BMSC) differentiation, both Wnt signaling and the development of a rigid cytoskeleton promote commitment to the osteoblastic over adipogenic lineage. β-catenin plays a critical role in the Wnt signaling pathway to facilitate downstream effects on gene expression. We...

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Udgivet i:J Bone Miner Res
Main Authors: Sen, Buer, Paradise, Christopher R, Xie, Zhihui, Sankaran, Jeyantt, Uzer, Gunes, Styner, Maya, Meyer, Mark, Dudakovic, Amel, van Wijnen, Andre J, Rubin, Janet
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295671/
https://ncbi.nlm.nih.gov/pubmed/32022326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3975
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