High-Fidelity Single Molecule Quantification in a Flow Cytometer Using Multiparametric Optical Analysis

Microfluidic techniques are widely used for high-throughput quantification and discrete analysis of micron-scale objects but are difficult to apply to molecular-scale targets. Instead, single-molecule methods primarily rely on low-throughput microscopic imaging of immobilized molecules. Here we repo...

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Udgivet i:ACS Nano
Main Authors: Smith, Lucas D., Liu, Yang, Zahid, Mohammad U., Canady, Taylor D., Wang, Liang, Kohli, Manish, Cunningham, Brian T., Smith, Andrew M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295608/
https://ncbi.nlm.nih.gov/pubmed/31971776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b09498
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