Microneutralization assay titer correlates analysis in two phase 3 trials of the CYD-TDV tetravalent dengue vaccine in Asia and Latin America

We previously showed that Month 13 50% plaque reduction neutralization test (PRNT(50)) neutralizing antibody (nAb) titers against dengue virus (DENV) correlated with vaccine efficacy (VE) of CYD-TDV against symptomatic, virologically-confirmed dengue (VCD) in the CYD14 and CYD15 Phase 3 trials. Whil...

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Publicado en:PLoS One
Main Authors: Carpp, Lindsay N., Fong, Youyi, Bonaparte, Matthew, Moodie, Zoe, Juraska, Michal, Huang, Ying, Price, Brenda, Zhuang, Yingying, Shao, Jason, Zheng, Lingyi, Chambonneau, Laurent, Small, Robert, Sridhar, Saranya, DiazGranados, Carlos A., Gilbert, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295445/
https://ncbi.nlm.nih.gov/pubmed/32542024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234236
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