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Immunotherapy in colorectal cancer: rationale, challenges and potential

Following initial successes in melanoma treatment, immunotherapy has rapidly become established as a major treatment modality for multiple types of solid cancers, including a subset of colorectal cancers (CRCs). Two programmed cell death 1 (PD1)-blocking antibodies, pembrolizumab and nivolumab, have...

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Detalhes bibliográficos
Publicado no:Nat Rev Gastroenterol Hepatol
Main Authors: Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Diaz, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7295073/
https://ncbi.nlm.nih.gov/pubmed/30886395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41575-019-0126-x
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