RNF8 induces β-catenin-mediated c-Myc expression and promotes colon cancer proliferation

DNA damage signals transducer RING finger protein 8 (RNF8) is involved in maintaining genomic stability by facilitating the repair of DNA double-strand breaks (DSB) via ubiquitin signaling. By analyzing the TCGA database and colon cancer tissue microarrays, we found that the expression level of RNF8...

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Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Ren, Ling, Zhou, Tingting, Wang, Yang, Wu, Yanmei, Xu, Hongde, Liu, Jingwei, Dong, Xiang, Yi, Fei, Guo, Qiqiang, Wang, Zhuo, Li, Xiaoman, Bai, Ning, Guo, Wendong, Guo, Min, Jiang, Bo, Wu, Xuan, Feng, Yanling, Song, Xiaoyu, Zhang, Siyi, Zhao, Yue, Cao, Liu, Han, Shuai, Xing, Chengzhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294952/
https://ncbi.nlm.nih.gov/pubmed/32549753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.44119
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