Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy

Oncolytic viruses (OVs), known for their cancer-killing characteristics, also overturn tumor-associated defects in antigen presentation through the MHC class I pathway and induce protective neo-antitumor CD8 T cell responses. Nonetheless, whether OVs shape the tumor MHC-I ligandome remains unknown....

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Bibliografske podrobnosti
izdano v:J Proteome Res
Main Authors: Murphy, J. Patrick, Kim, Youra, Clements, Derek R., Konda, Prathyusha, Schuster, Heiko, Kowalewski, Daniel J., Paulo, Joao A., Cohen, Alejandro M., Stevanovic, Stefan, Gygi, Steven P., Gujar, Shashi
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294931/
https://ncbi.nlm.nih.gov/pubmed/31095916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00173
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