TORC1 signaling regulates cytoplasmic pH through Sir2 in yeast

Glucose controls the phosphorylation of silent information regulator 2 (Sir2), a NAD(+)‐dependent protein deacetylase, which regulates the expression of the ATP‐dependent proton pump Pma1 and replicative lifespan (RLS) in yeast. TORC1 signaling, which is a central regulator of cell growth and lifesp...

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Vydáno v:Aging Cell
Hlavní autoři: Devare, Mayur Nimbadas, Kim, Yeong Hyeock, Jung, Joohye, Kang, Woo Kyu, Kwon, Ki‐Sun, Kim, Jeong‐Yoon
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294778/
https://ncbi.nlm.nih.gov/pubmed/32449834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13151
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