Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from Trypanosoma cruzi

[Image: see text] Chagas disease is a parasitic infection affecting millions of people across Latin America, imposing a dramatic socioeconomic burden. Despite the availability of drugs, nifurtimox and benznidazole, lack of efficacy and incidence of side-effects prompt the identification of novel, ef...

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Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Fredo Naciuk, Fabrício, do Nascimento Faria, Jéssica, Gonçalves Eufrásio, Amanda, Torres Cordeiro, Artur, Bruder, Marjorie
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294730/
https://ncbi.nlm.nih.gov/pubmed/32551008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00106
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