Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

BACKGROUND: Aucubin (Au), an iridoid glycoside from natural plants, has antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain injury (TBI) model remain unknown. We explored the potential role of Au in an H(2)O(2)-induced oxidant damage in primary cortical neuro...

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Опубликовано в: :J Neuroinflammation
Главные авторы: Wang, Han, Zhou, Xiao-Ming, Wu, Ling-Yun, Liu, Guang-Jie, Xu, Wei-Dong, Zhang, Xiang-Sheng, Gao, Yong-Yue, Tao, Tao, Zhou, Yan, Lu, Yue, Wang, Juan, Deng, Chu-Lei, Zhuang, Zong, Hang, Chun-Hua, Li, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294631/
https://ncbi.nlm.nih.gov/pubmed/32539839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01863-9
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