Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment

BACKGROUND: Pediatric acute myeloid leukemia (AML) with t(8;21) (q22;q22) is classified as a low-risk group. However, relapse is still the main factor affecting survival. We aimed to investigate the effect of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on reducing recurrence and i...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Hu, Guan-hua, Cheng, Yi-fei, Lu, Ai-dong, Wang, Yu, Zuo, Ying-xi, Yan, Chen-hua, Wu, Jun, Sun, Yu-qian, Suo, Pan, Chen, Yu-hong, Chen, Huan, Jia, Yue-ping, Liu, Kai-yan, Han, Wei, Xu, Lan-ping, Zhang, Le-ping, Huang, Xiao-jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294617/
https://ncbi.nlm.nih.gov/pubmed/32539815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07043-5
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