High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathy

Numerous risk factors for heart disease or dementia harbor over 10% valine plus glycine content. Interestingly, TDP-43 contains 6.0% valine and 13.3% glycine, and the buildup of this protein in the brains of patients with limbic-predominant age-related TDP-43 encephalopathy has dire consequences. Th...

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Detalhes bibliográficos
Publicado no:J Int Med Res
Main Authors: An, Shanshan, Zhang, Xiaoxiao, Shi, Yunfan, Zhang, Jiaming, Wan, Yulin, Wang, Yuchuan, Zhang, Ying, Liu, Qiuyun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Meta-Analysis and Systematic Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294501/
https://ncbi.nlm.nih.gov/pubmed/32529876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060520929853
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