Inhibition of PIM1 attenuates the stem cell–like traits of breast cancer cells by promoting RUNX3 nuclear retention

Finding out the driver gene critical for the maintenance of breast cancer stem cells (BrCSCs) is important for designing a new strategy to eradicate these cells to improve patient's prognosis. Here, in our study, we revealed that PIM1, an oncogenic serine‐threonine kinase and a well‐proven cont...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Liu, Hui, Chen, Cheng, Ma, Dongshen, Li, Yubing, Yin, Qianqian, Li, Qing, Xiang, Chenxi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294145/
https://ncbi.nlm.nih.gov/pubmed/32307917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15272
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