ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells

BACKGROUND: Elongation factor for RNA polymerase II 2 (ELL2) was reported as a putative tumor suppressor in the prostate. ELL2 is frequently down-regulated in prostatic adenocarcinoma specimens, and loss of ELL2 induced murine prostatic intraepithelial neoplasia and enhanced AR-positive prostate can...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Manag Res
Auteurs principaux: Wang, Zhi, Pascal, Laura E, Chandran, Uma R, Chaparala, Srilakshmi, Lv, Shidong, Ding, Hui, Qi, Lin, Wang, Zhou
Format: Artigo
Langue:Inglês
Publié: Dove 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294050/
https://ncbi.nlm.nih.gov/pubmed/32606936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S248854
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