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Structural approaches to pathway specific antimicrobial agents

This perspective provides an overview of the evolution of antibiotic discovery from a largely phenotypic-based effort, through an intensive structure-based design focus, to a more holistic approach today. The current focus on antibiotic development incorporates assay and discovery conditions that re...

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Publicat a:Transl Res
Autors principals: Johnson, Michael E., Fung, Leslie W.-M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293926/
https://ncbi.nlm.nih.gov/pubmed/32105648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2020.02.001
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