PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness

Although tumorigenesis is dependent on the reprogramming of cellular metabolism, the metabolic pathways engaged in the formation of metastases remain largely unknown. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) plays a pleiotropic role...

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Udgivet i:Cancer Res
Main Authors: Kaminski, Lisa, Torrino, Stéphanie, Dufies, Maeva, Djabari, Zied, Haider, Romain, Roustan, François-René, Jaune, Emilie, Laurent, Kathiane, Nottet, Nicolas, Michiels, Jean-François, Gesson, Maeva, Rocchi, Stéphane, Mazure, Nathalie M., Durand, Matthieu, Tanti, Jean-François, Ambrosetti, Damien, Clavel, Stephan, Ben-Sahra, Issam, Bost, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293888/
https://ncbi.nlm.nih.gov/pubmed/31064849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2043
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