PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness

Although tumorigenesis is dependent on the reprogramming of cellular metabolism, the metabolic pathways engaged in the formation of metastases remain largely unknown. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) plays a pleiotropic role...

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Publicado en:Cancer Res
Autores principales: Kaminski, Lisa, Torrino, Stéphanie, Dufies, Maeva, Djabari, Zied, Haider, Romain, Roustan, François-René, Jaune, Emilie, Laurent, Kathiane, Nottet, Nicolas, Michiels, Jean-François, Gesson, Maeva, Rocchi, Stéphane, Mazure, Nathalie M., Durand, Matthieu, Tanti, Jean-François, Ambrosetti, Damien, Clavel, Stephan, Ben-Sahra, Issam, Bost, Frédéric
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293888/
https://ncbi.nlm.nih.gov/pubmed/31064849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2043
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