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Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

Morphogenesis, tumor formation, and wound healing are regulated by tissue rigidity. Focal adhesion behavior is locally regulated by stiffness; however, how cells globally adapt, detect, and respond to rigidity remains unknown. Here, we studied the interplay between the rheological properties of the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Doss, Bryant L., Pan, Meng, Gupta, Mukund, Grenci, Gianluca, Mège, René-Marc, Lim, Chwee Teck, Sheetz, Michael P., Voituriez, Raphaël, Ladoux, Benoît
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293595/
https://ncbi.nlm.nih.gov/pubmed/32444491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917555117
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