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The interactions between cGAS-STING pathway and pathogens
Cytosolic DNA is an indicator of pathogen invasion or DNA damage. The cytosolic DNA sensor cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) detects DNA and then mediates downstream immune responses through the molecule stimulator of interferon genes (STING, also known a...
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| Publié dans: | Signal Transduct Target Ther |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293265/ https://ncbi.nlm.nih.gov/pubmed/32532954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0198-7 |
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