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Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia

Anaemia is frequently present in patients with acute myocardial infarction (AMI) and contributes to an adverse prognosis. We hypothesised that, besides reduced oxygen carrying capacity, anaemia is associated with (1) red blood cell (RBC) dysfunction and a reduced circulating nitric oxide (NO) pool,...

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Veröffentlicht in:Basic Res Cardiol
Hauptverfasser: Wischmann, Patricia, Kuhn, Viktoria, Suvorava, Tatsiana, Muessig, Johanna M., Fischer, Jens W., Isakson, Brant E., Haberkorn, Sebastian M., Flögel, Ulrich, Schrader, Jürgen, Jung, Christian, Cortese-Krott, Miriam M., Heusch, Gerd, Kelm, Malte
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293199/
https://ncbi.nlm.nih.gov/pubmed/32533377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-020-0799-x
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