eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function

As cells encounter adverse environmental conditions, such as hypoxia, oxidative stress or nutrient deprivation, they trigger stress response pathways to protect themselves until transient stresses have passed. Inhibition of translation is a key component of such cellular stress responses and mountin...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Lyons, Shawn M, Kharel, Prakash, Akiyama, Yasutoshi, Ojha, Sandeep, Dave, Dhwani, Tsvetkov, Vladimir, Merrick, William, Ivanov, Pavel, Anderson, Paul
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293036/
https://ncbi.nlm.nih.gov/pubmed/32374873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa336
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