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Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca(2+)-channel

The bronchodilator effects of Roflumilast “a selective phosphodiesterase type-4 (PDE4)” inhibitor studied in this experimental protocol. The spiral strips of isolated guinea-pig tracheal chains mounted in organ bath and maintained in Krebs solution ventilated with carbogen at 32 °C and in Ca(++) res...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Imam, Faisal, Rehman, Najeeb Ur, Ansari, Mohd Nazam, Qamar, Wajhul, Afzal, Muhammad, Alharbi, Khalid Saad
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292871/
https://ncbi.nlm.nih.gov/pubmed/32550801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2020.04.011
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