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Validating the validation: reanalyzing a large-scale comparison of deep learning and machine learning models for bioactivity prediction

Machine learning methods may have the potential to significantly accelerate drug discovery. However, the increasing rate of new methodological approaches being published in the literature raises the fundamental question of how models should be benchmarked and validated. We reanalyze the data generat...

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Detalhes bibliográficos
Publicado no:J Comput Aided Mol Des
Main Authors: Robinson, Matthew C., Glen, Robert C., Lee, Alpha A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292817/
https://ncbi.nlm.nih.gov/pubmed/31960253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00274-0
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