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THE MOUSE-EQUIVALENT OF THE HUMAN BDNF VAL66MET POLYMORPHISM INCREASES DORSAL HIPPOCAMPAL VOLUME AND DOES NOT INTERACT WITH DEVELOPMENTAL ETHANOL EXPOSURE
A relatively common polymorphism in the human brain-derived neurotrophic factor (BDNF) gene (Val66Met, which corresponds to Val68Met in mice) has been shown to modulate cognitive function and vulnerability to mental health disorders. This substitution impairs trafficking and activity-dependent relea...
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| Published in: | Alcohol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7292775/ https://ncbi.nlm.nih.gov/pubmed/32224221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2020.03.005 |
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