A NOVEL PHARMACOTHERAPY APPROACH USING P-GLYCOPROTEIN (PGP/ABCB1) EFFLUX INHIBITOR COMBINED WITH IVERMECTIN TO REDUCE ALCOHOL DRINKING, PREFERENCE IN MICE

Alcohol Use Disorder (AUD) has a major national impact, affecting over 18 million people, causing approximately 88,000 deaths and costing upward of $220 billion annually in the US. Unfortunately, FDA-approved AUD pharmaceuticals are few, and clinical benefits are mostly ineffective in patients suffe...

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Bibliografiske detaljer
Udgivet i:Alcohol
Main Authors: Silva, Joshua, Khoja, Sheraz, Asatryan, Liana, Pacifici, Eunjoo, Davies, Daryl L.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292774/
https://ncbi.nlm.nih.gov/pubmed/32278067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2020.03.013
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