Multiplexed whole-animal imaging with reversibly switchable optoacoustic proteins

We introduce two photochromic proteins for cell-specific in vivo optoacoustic (OA) imaging with signal unmixing in the temporal domain. We show highly sensitive, multiplexed visualization of T lymphocytes, bacteria, and tumors in the mouse body and brain. We developed machine learning–based software...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Mishra, Kanuj, Stankevych, Mariia, Fuenzalida-Werner, Juan Pablo, Grassmann, Simon, Gujrati, Vipul, Huang, Yuanhui, Klemm, Uwe, Buchholz, Veit R., Ntziachristos, Vasilis, Stiel, Andre C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2020
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292636/
https://ncbi.nlm.nih.gov/pubmed/32582850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz6293
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