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Targeted de novo centromere formation in Drosophila reveals plasticity and maintenance potential of CENP-A chromatin
Centromeres are essential for accurate chromosome segregation and are marked by CENP-A nucleosomes. Mis-targeted CENP-A chromatin has been shown to seed centromeres at non-centromeric DNA. However, the requirements for such de novo centromere formation and transmission in vivo remain unknown. Here,...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7292339/ https://ncbi.nlm.nih.gov/pubmed/32049040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.01.005 |
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