Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase‐2

AIM: Tryptophan hydroxylase 2 (Tph2) is a rate‐limiting enzyme for the biosynthesis of 5‐hydroxytryptamine (5‐HT, serotonin). Previous studies have reported that C1473G polymorphism of the murine Tph2 gene leads to decreased 5‐HT levels in the brain and abnormal behavioral phenotypes, such as impair...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacol Rep
Main Authors: Koshimizu, Hisatsugu, Hirata, Nao, Takao, Keizo, Toyama, Keiko, Ichinose, Takashi, Furuya, Shigeki, Miyakawa, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Micro Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292325/
https://ncbi.nlm.nih.gov/pubmed/30472790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12041
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