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Tropomyosin isoforms regulate cofilin 1 activity by modulating actin filament conformation

Tropomyosin and cofilin are involved in the regulation of actin filament dynamic polymerization and depolymerization. Binding of cofilin changes actin filaments structure, leading to their severing and depolymerization. Non-muscle tropomyosin isoforms were shown before to differentially regulate the...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Ostrowska-Podhorodecka, Zofia, Śliwinska, Małgorzata, Reisler, Emil, Moraczewska, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291848/
https://ncbi.nlm.nih.gov/pubmed/31996302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108280
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