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Tropomyosin isoforms regulate cofilin 1 activity by modulating actin filament conformation

Tropomyosin and cofilin are involved in the regulation of actin filament dynamic polymerization and depolymerization. Binding of cofilin changes actin filaments structure, leading to their severing and depolymerization. Non-muscle tropomyosin isoforms were shown before to differentially regulate the...

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Bibliographische Detailangaben
Veröffentlicht in:Arch Biochem Biophys
Hauptverfasser: Ostrowska-Podhorodecka, Zofia, Śliwinska, Małgorzata, Reisler, Emil, Moraczewska, Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291848/
https://ncbi.nlm.nih.gov/pubmed/31996302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108280
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